This course provides a practical introduction to the analysis and visualisation of ATAC-seq data. Building on the foundations of Next-Generation Sequencing, it will help you understand how ATAC-seq can be used to explore chromatin accessibility and generate meaningful insights for biomedical research, moving from processed NGS outputs to biological interpretation.
Through flexible, hands-on learning in R and RStudio, you will read ATAC-seq data, annotate genomic features, visualise results, call peaks and perform differential accessibility analysis.
By the end of the course, you will understand what ATAC-seq data can offer, how bulk ATAC-seq analysis is carried out, and how to apply these methods using example datasets prepared through established NF-core ATAC-seq pipelines.